Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Cholestenone-d5

Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].

Product Specifications

CAS Number

72560-60-2

Product Name Alternative

4-Cholesten-3-one-d5

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

99.42

Solubility

10 mM in DMSO|Ethanol : 50mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)C

Molecular Formula

C27H39D5O

Molecular Weight

389.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Neuvonen M, et, al. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. PLoS One. 2014 Aug 26;9 (8) :e103743.|[3]Rosenheim O, et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37 (4) :513-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Preserved Blood RNA Purification Kit II (For use with PAXgene Blood RNA Tubes)
43500 50 Preparations

Preserved Blood RNA Purification Kit II (For use with PAXgene Blood RNA Tubes)

Sign In for Pricing
View Details
Trimedlure
TRC-T896515-500MG 500 mg

Trimedlure

Sign In for Pricing
View Details
Pdcd1 Mouse Gene Knockout Kit (CRISPR)
KN312990LP 1 Kit

Pdcd1 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
TRIM22 (NM_006074) Human Over-expression Lysate
LC401829 20 µg

TRIM22 (NM_006074) Human Over-expression Lysate

Sign In for Pricing
View Details
Dicer (DICER1) Human Gene Knockout Kit (CRISPR)
KN211804RB 1 Kit

Dicer (DICER1) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Deslorelin Monoacetate
TRC-D577310-1G 1 g

Deslorelin Monoacetate

Sign In for Pricing
View Details