Maculatin 1.1 (TFA)
Maculatin 1.1 TFA is an antimicrobial peptide with an MIC against Staphylococcus aureus of 7 μM. Maculatin 1.1 TFA can perforate the bacterial membrane of Staphylococcus aureus, causing bacterial death[1].
Product Specifications
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/maculatin-1-1-tfa.html
Purity
96.93
Solubility
10 mM in DMSO
Smiles
NCC(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C103H161N27O23.xC2HF3O2
Molecular Weight
2145.55 (free base)
References & Citations
[1]Sani MA, et al. Maculatin 1.1 disrupts Staphylococcus aureus lipid membranes via a pore mechanism. Antimicrob Agents Chemother. 2013 Aug;57 (8) :3593-600.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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