2’-Fluoro-2’-deoxy-ara-C (Bz) -3’-phosphoramidite
2’-Fluoro-2’-deoxy-ara-C (Bz) -3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-fluoro-2-deoxy-ara-c-bz-3-phosphoramidite.html
Purity
99.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F
Molecular Formula
C46H51FN5O8P
Molecular Weight
851.90
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154414/2-Fluoro-2-deoxy-ara-C-Bz-3-phosphoramidite-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154414/2-Fluoro-2-deoxy-ara-C-Bz-3-phosphoramidite-SDS-MedChemExpress.pdf
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[1404463-12-2]
Available Sizes
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