Zuclomiphene (citrate)

Zuclomiphene citrate is a cis isomer of Clomiphene citrate (HY-B0463) . Zuclomiphene citrate is orally active and has an antiestrogenic effect. Zuclomiphene can reduce cholesterol levels. Zuclomiphene citrate can be for the researches of endocrinology and metabolic disease[1][2].

Product Specifications

CAS Number

[7619-53-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/zuclomiphene-citrete.html

Concentration

10mM

Purity

98.09

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

Cl/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(CC)CC)C=C2)/C3=CC=CC=C3.O=C(CC(C(O)=O)(O)CC(O)=O)O

Molecular Formula

C32H36ClNO8

Molecular Weight

598.08

Precautions

H302, H315, H319, H335

References & Citations

[1]Fontenot GK, et al. Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice. BJU Int. 2016 Feb;117 (2) :344-50.|[2]Ramsey RB, et al. Effects of zuclomiphene in combination with triparanol and ay-9944 on developing rat CNS morphology and biochemistry. Acta Neuropathol. 1977 Jul 15;39 (1) :97-100.