Macropin

Macropin (MAC-1 peptide) is an antimicrobial peptide found in the venom of the solitary bee Macropis fulvipes. Macropin has antibacterial activity against both Gram-positive and Gram-negative bacteria, and also exhibits inhibitory activity against fungi and moderate hemolytic activity against human erythrocytes. Macropin can be used in research on anti-infective therapy[1].

Product Specifications

CAS Number

1382853-39-5

Product Name Alternative

MAC-1 peptide

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/macropin.html

Smiles

CC(C)C[C@@H](C(N)=O)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCSC)NC(CNC([C@@H](NC(CN)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C68H121N17O13S

Molecular Weight

1416.86

References & Citations

[1]Monincová L, et al. Structure–activity study of macropin, a novel antimicrobial peptide from the venom of solitary bee Macropis fulvipes (Hymenoptera: Melittidae) [J]. Journal of Peptide Science, 2014, 20 (6) : 375-384.