N-Arachidonyl maleimide
N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM[1].
Product Specifications
CAS Number
[876305-42-9]
UNSPSC
12352005
Hazard Statement
H317
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/n-arachidonyl-maleimide.html
Concentration
10mM
Purity
98.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C=C1)N(CCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)C1=O
Molecular Formula
C24H35NO2
Molecular Weight
369.54
Precautions
H317
References & Citations
[1]Susanna M Saario, et al. Characterization of the Sulfhydryl-Sensitive Site in the Enzyme Responsible for Hydrolysis of 2-arachidonoyl-glycerol in Rat Cerebellar Membranes. Chem Biol. 2005 Jun;12 (6) :649-56.|[2]James J Burston, et al. N-arachidonyl Maleimide Potentiates the Pharmacological and Biochemical Effects of the Endocannabinoid 2-arachidonylglycerol Through Inhibition of Monoacylglycerol Lipase. J Pharmacol Exp Ther. 2008 Nov;327 (2) :546-53.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1125405-01 0.02 mg (E-Coli)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details 
MBS1125405-02 0.1 mg (E-Coli)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details MBS1125405-03 0.02 mg (Yeast)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details MBS1125405-04 0.1 mg (Yeast)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details MBS1125405-05 0.02 mg (Baculovirus)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details 
MBS1125405-06 0.02 mg (Mammalian-Cell)
Recombinant Schizosaccharomyces pombe Uncharacterized protein C651.04 (SPBC651.04)
Sign In for Pricing
View Details