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TLR8 agonist 5

TLR8 agonist 5 is a potent TLR8 agonist with an EC50 value of 20 nM for HEK-Blue hTLR8. TLR8 agonist 5 activates the immune response[1].

Product Specifications

CAS Number

2413016-41-6

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tlr8-agonist-5.html

Purity

98.38

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC(C)(C)C(NCCOC(C)(CN1C(COCC)=NC2=C1C3=C(C=CC=C3)N=C2N)C)=O)OCC4=CC=CC=C4

Molecular Formula

C31H40N6O5

Molecular Weight

576.69

References & Citations

[1]Smith SW, et, al. Benzazepine compounds, conjugates, and uses thereof. WO2020056194.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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