TLR8 agonist 5
TLR8 agonist 5 is a potent TLR8 agonist with an EC50 value of 20 nM for HEK-Blue hTLR8. TLR8 agonist 5 activates the immune response[1].
Product Specifications
CAS Number
2413016-41-6
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-5.html
Purity
98.38
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC(C)(C)C(NCCOC(C)(CN1C(COCC)=NC2=C1C3=C(C=CC=C3)N=C2N)C)=O)OCC4=CC=CC=C4
Molecular Formula
C31H40N6O5
Molecular Weight
576.69
References & Citations
[1]Smith SW, et, al. Benzazepine compounds, conjugates, and uses thereof. WO2020056194.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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