Protein kinase inhibitor H-7 (dihydrochloride)
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) [1].
Product Specifications
CAS Number
108930-17-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protein-kinase-inhibitor-h-7-dihydrochloride.html
Purity
99.63
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=S(C1=CC=CC2=C1C=CN=C2)(N3C(C)CNCC3)=O.[H]Cl.[H]Cl
Molecular Formula
C14H19Cl2N3O2S
Molecular Weight
364.29
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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