Nampt activator-1
Nampt activator-1 (compound 1) is a potent Nicotinamide phosphoribosyltransferase (NAMPT) activator, with EC50 of 3.3-3.7 μM[1].
Product Specifications
CAS Number
701929-65-9
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nampt-activator-1.html
Purity
98.63
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(OCC)C1=CC=C(NC(NCC2=CC=NC=C2)=O)C=C1
Molecular Formula
C16H17N3O3
Molecular Weight
299.32
References & Citations
[1]Akiu M, et al. Discovery of 1-[2- (1-methyl-1H-pyrazol-5-yl) -[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3- (pyridin-4-ylmethyl) urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.[J]. Bioorganic & medicinal chemistry letters, 2021, 43:128048.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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