Nampt activator-1
Nampt activator-1 (compound 1) is a potent Nicotinamide phosphoribosyltransferase (NAMPT) activator, with EC50 of 3.3-3.7 μM[1].
Product Specifications
CAS Number
701929-65-9
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nampt-activator-1.html
Purity
98.63
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(OCC)C1=CC=C(NC(NCC2=CC=NC=C2)=O)C=C1
Molecular Formula
C16H17N3O3
Molecular Weight
299.32
References & Citations
[1]Akiu M, et al. Discovery of 1-[2- (1-methyl-1H-pyrazol-5-yl) -[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3- (pyridin-4-ylmethyl) urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.[J]. Bioorganic & medicinal chemistry letters, 2021, 43:128048.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY428009 100 µg
SMC6L1 (SMC6) (NM_001142286) Human Over-expression Lysate
Sign In for Pricing
View Details 
LY424182 100 µg
Apc11 (ANAPC11) (NM_001002245) Human Over-expression Lysate
Sign In for Pricing
View Details 
