7-Ketositosterol

7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.) . 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394) -induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].

Product Specifications

CAS Number

[2034-74-4]

UNSPSC

12352211

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-ketositosterol.html

Purity

99.9

Solubility

DMF : 12 mg/mL (ultrasonic; warming)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3=O)C

Molecular Formula

C29H48O2

Molecular Weight

428.69

References & Citations

[1]Lee D, et al. Identification of Renoprotective Phytosterols from Mulberry (Morus alba) Fruit against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants (Basel) . 2021 Nov 17;10 (11) :2481.