Neuropeptide FF

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF (1) and NPFF (2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].

Product Specifications

CAS Number

[99566-27-5]

Product Name Alternative

NPFF

UNSPSC

12352209

Target

Neuropeptide FF Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/neuropeptide-ff.html

Purity

98.80

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C54H76N14O10

Molecular Weight

1081.27

References & Citations

[1]Mankus JV, et al. Nonpeptide ligands of neuropeptide FF: current status and structural insights. Future Med Chem. 2012 Jun;4 (9) :1085-92.|[2]Jhamandas JH, et al. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne) . 2013 Feb 7;4:8.