Nudifloramide
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly (ADP-ribose) polymerase (PARP-1) activity in vitro[1].
Product Specifications
CAS Number
[701-44-0]
Product Name Alternative
2PY
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; PARP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide.html
Purity
99.94
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)
Smiles
O=C(C(C=C1)=CN(C)C1=O)N
Molecular Formula
C7H8N2O2
Molecular Weight
152.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May; (84) :S19-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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