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Nudifloramide

Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly (ADP-ribose) polymerase (PARP-1) activity in vitro[1].

Product Specifications

CAS Number

[701-44-0]

Product Name Alternative

2PY

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; PARP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide.html

Purity

99.94

Solubility

DMSO : 62.5 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

Smiles

O=C(C(C=C1)=CN(C)C1=O)N

Molecular Formula

C7H8N2O2

Molecular Weight

152.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May; (84) :S19-21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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