Caspase-9 Inhibitor III
Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1].
Product Specifications
CAS Number
403848-57-7
Product Name Alternative
Ac-LEHD-cmk
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/caspase-9-inhibitor-iii.html
Purity
99.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C)C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CC(O)=O)C(CCl)=O)=O)CC1=CN=CN1)=O)=O
Molecular Formula
C24H35ClN6O9
Molecular Weight
587.02
References & Citations
[1]Sodhi RK, et, al. Protective effects of caspase-9 and poly (ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury. Arch Pharm Res. 2009 Jul;32 (7) :1037-43. |[2]Castro MM, et, al. Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2. Biochem Pharmacol. 2013 Aug 15;86 (4) :469-75.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 9
Available Sizes
Frequently Asked Questions
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