Caspase-9 Inhibitor III

Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1].

Product Specifications

CAS Number

[403848-57-7]

Product Name Alternative

Ac-LEHD-cmk

UNSPSC

12352005

Target

Caspase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/caspase-9-inhibitor-iii.html

Purity

99.00

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC(C)C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CC(O)=O)C(CCl)=O)=O)CC1=CN=CN1)=O)=O

Molecular Formula

C24H35ClN6O9

Molecular Weight

587.02

References & Citations

[1]Sodhi RK, et, al. Protective effects of caspase-9 and poly (ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury. Arch Pharm Res. 2009 Jul;32 (7) :1037-43. |[2]Castro MM, et, al. Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2. Biochem Pharmacol. 2013 Aug 15;86 (4) :469-75.