Gallic aldehyde

Gallic aldehyde (3,4,5-Trihydroxybenzaldehyde) is a phenolic aldehyde. Gallic aldehyde can be isolated from Geum japonicum. Gallic aldehyde inhibits the gelatinolytic activity and expression of MMP-9. Gallic aldehyde also inhibits ERK1/2, p38, and JNK. Gallic aldehyde has potent anti-HSV-1 and antioxidant activities. Gallic aldehyde also exhibits antibacterial activity against Oenococcus oeni VF[1][2][3][4].

Product Specifications

CAS Number

[13677-79-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ERK; HSV; JNK; MMP; p38 MAPK

Type

Reference compound

Related Pathways

Anti-infection; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gallic-aldehyde.html

Purity

99.95

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=CC1=CC(O)=C(O)C(O)=C1

Molecular Formula

C7H6O4

Molecular Weight

154.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Kadota S, et al. A New Hydrolyzable Tannin from Geum japonicum and Its Antiviral Activity[J]. Heterocycles, 1994, 38 (1) :167-175.|[2]Miwa H, et al. Liquid chromatographic determination of free and total fatty acids in milk and milk products as their 2-nitrophenylhydrazides. J Chromatogr. 1990 Dec 7;523:235-46. |[3]Thomas SC, et al. Phytotoxicity and hormesis in common mobile organic compounds in leachates of wood-derived biochars. Biochar. 2024;6 (1) :51. |[4]Arturo Anadon, et al. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) ; Scientific Opinion on Flavouring Group Evaluation 06, Revision 2 (FGE.06Rev2) : Straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4. EFSA Journal 2011; 9 (3) :1844. [78 pp.].