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N-Boc-PEG2-bromide

N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

165963-71-3

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-peg2-bromide.html

Purity

98.19

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(OC(NCCOCCOCCBr)=O)C

Molecular Formula

C11H22BrNO4

Molecular Weight

312.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Alex Cortez, et al. Antibody conjugates comprising toll-like receptor agonist and combination therapies. WO2018198091A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

Available Sizes

Frequently Asked Questions

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