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Dimiracetam

Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201) -induced neuropathy in cold stimulation rat models[1].

Product Specifications

CAS Number

[126100-97-8]

Product Name Alternative

NT-11624

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dimiracetam.html

Purity

98.0

Solubility

10 mM in DMSO|DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1N(C(CC1)N2)CC2=O

Molecular Formula

C6H8N2O2

Molecular Weight

140.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Di Cesare Mannelli L, et al. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7.|[2]Di Cesare Mannelli L, et al. A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin. Cancer Chemother Pharmacol. 2017 Dec;80 (6) :1091-1103.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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