MRE 0094
MRE 0094 (Sonedenoson) is a selective activator for adenosine receptor A2A, with a Ki of 490 nM. MRE 0094 exhibits anti-platelet and anti-inflammatory activities[1].
Product Specifications
CAS Number
[131865-88-8]
Product Name Alternative
Sonedenoson
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mre-0094.html
Purity
99.79
Smiles
NC1=NC(OCCC2=CC=C(Cl)C=C2)=NC3=C1N=CN3[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O
Molecular Formula
C18H20ClN5O5
Molecular Weight
421.83
References & Citations
[1]Boncler M, et al., Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists. Vascul Pharmacol. 2019 Feb;113:47-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Adenosine A2A receptor (A2AR) ; Adenosine A2B receptor (A2BR)
Available Sizes
Curated Selection
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