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MRE 0094

MRE 0094 (Sonedenoson) is a selective activator for adenosine receptor A2A, with a Ki of 490 nM. MRE 0094 exhibits anti-platelet and anti-inflammatory activities[1].

Product Specifications

CAS Number

[131865-88-8]

Product Name Alternative

Sonedenoson

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mre-0094.html

Purity

99.79

Smiles

NC1=NC(OCCC2=CC=C(Cl)C=C2)=NC3=C1N=CN3[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O

Molecular Formula

C18H20ClN5O5

Molecular Weight

421.83

References & Citations

[1]Boncler M, et al., Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists. Vascul Pharmacol. 2019 Feb;113:47-56.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

Adenosine A2A receptor (A2AR) ; Adenosine A2B receptor (A2BR)

Available Sizes

Curated Selection

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