Ethyl glucuronide

Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4[1][2].

Product Specifications

CAS Number

[17685-04-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Toll-like Receptor (TLR)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ethyl-glucuronide.html

Purity

99.22

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

OC([C@@H]1[C@H]([C@@H]([C@@H](O)[C@H](OCC)O1)O)O)=O

Molecular Formula

C8H14O7

Molecular Weight

222.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Małkowska A, et al., The influence of caffeine on ethyl glucuronide levels in rat serum and in rat hair. Pharmacol Rep. 2018 Oct;70 (5) :831-836.|[2]Lewis SS, et al., Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain Behav Immun. 2013 May;30:24-32.