3-Dehydrotrametenolic acid
Product Specifications
UNSPSC Description
3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2].
Target Antigen
Apoptosis; Lactate Dehydrogenase
Type
Natural Products
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-dehydrotrametenolic-acid.html
Purity
99.86
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C(O)=O)CC/C=C(C)\C)CC[C@](C)4C3=CC[C@@]12[H]
Molecular Weight
454.68
References & Citations
[1]De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86.|[2]Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2177/3-Dehydrotrametenolic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2177/3-Dehydrotrametenolic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
29220-16-4
Available Sizes
Curated Selection
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