Chloroxine

Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp[1][2].

Product Specifications

CAS Number

[773-76-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H318, H335

Target

Antibiotic; Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Chloroxine.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

OC1=C2N=CC=CC2=C(Cl)C=C1Cl

Molecular Formula

C9H5Cl2NO

Molecular Weight

214.05

Precautions

H302, H315, H318, H335

References & Citations

[1]Renjie X, et al. Solubility modelling, solvent effect and preferential solvation of carbendazim in aqueous co-solvent mixtures of, N, N -dimethylformamide, methanol, ethanol and, n -propanol. J. Chem. Thermodynamics 138 (2019) 288–296.|[2]Chloroxine (Topical) . Dec 27, 2018