CXCL8 (54-72)
Product Specifications
UNSPSC Description
CXCL8 (54-72) is a C-terminal peptide based on the chemokine CXCL8. CXCL8 (54-72) has an interaction between a long and highly positively charged C-terminal region and a negative charge on the GAG that binds to the GAG. CXCL8 (54-72) can inhibit the adhesion and migration of neutrophils and adhesion of endothelial cells. CXCL8 (54-72) can be used to study chemokines in inflammatory response[1].
Target Antigen
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cxcl8-54-72.html
Purity
99.03
Solubility
10 mM in DMSO
Smiles
O=C(C)N[C@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](CC(N)=O)C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](CCCCN)C(N[C@H](C(N[C@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
2401.72
References & Citations
[1]Martínez‐Burgo B, et al. AC‐terminal CXCL 8 peptide based on chemokine–glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation[J]. Immunology, 2019, 157(2): 173-184.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10300/CXCL8-54-72-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10300/CXCL8-54-72-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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