CXCL8 (54-72)

CXCL8 (54-72) is a C-terminal peptide based on the chemokine CXCL8. CXCL8 (54-72) has an interaction between a long and highly positively charged C-terminal region and a negative charge on the GAG that binds to the GAG. CXCL8 (54-72) can inhibit the adhesion and migration of neutrophils and adhesion of endothelial cells. CXCL8 (54-72) can be used to study chemokines in inflammatory response[1].

Product Specifications

Product Name Alternative

IL-8 (54-72)

UNSPSC

12352209

Target

CXCR

Type

Peptides

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cxcl8-54-72.html

Purity

99.03

Solubility

10 mM in DMSO

Smiles

O=C(C)N[C@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](CC(N)=O)C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](CCCCN)C(N[C@H](C(N[C@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C107H173N33O30

Molecular Weight

2401.72

References & Citations

[1]Martínez‐Burgo B, et al. AC‐terminal CXCL 8 peptide based on chemokine–glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation[J]. Immunology, 2019, 157 (2) : 173-184.