HA130
HA130 is a selective autotaxin (ATX) inhibitor with an IC50 of 28 nM.
Product Specifications
CAS Number
1229652-21-4
UNSPSC
12352005
Hazard Statement
H302
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HA130.html
Purity
99.46
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1N(CC2=CC=C(F)C=C2)C(S/C1=C\C3=CC=C(OCC4=CC(B(O)O)=CC=C4)C=C3)=O
Molecular Formula
C24H19BFNO5S
Molecular Weight
463.29
Precautions
H302
References & Citations
[1]Zhang Y, et al. Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. J Immunol. 2012 Oct 15;189 (8) :3914-3924.|[2]Bai Z, et al. Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by theautotaxin/lysophosphatidic acid axis. J Immunol. 2013 Mar 1;190 (5) :2036-2048.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin
Available Sizes
Frequently Asked Questions
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