Human DLL3 Protein, Llama IgG2b Fc Tag

Human DLL3 Protein, Llama IgG2b Fc Tag (DL3-H525x) is expressed from human 293 cells (HEK293) . It contains AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1) .

Product Specifications

Background

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

Specifications

This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 76.6 kDa. The protein migrates as 75-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9NYJ7-1

Expression Region

Ala 27 - Leu 492

Host

HEK293

Target

DLL3

Conjugation

Unconjugated

Tag

C-LlamaFc (LlamaIgG2b)

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.2 EU per μg

Purity

90%

Bioactivity

Immobilized Human DLL3 Protein, Llama IgG2b Fc Tag (Cat. No. DL3-H525x) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 (Cat. No. AM186) with a linear range of 0.39-6.25 ng/mL (QC tested).