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Tos-O-C4-NH-Boc

Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs, such as BSJ-03-204.

Product Specifications

CAS Number

180851-50-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tos-o-c4-nh-boc.html

Purity

97.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)NCCCCOS(=O)(C1=CC=C(C)C=C1)=O

Molecular Formula

C16H25NO5S

Molecular Weight

343.44

Precautions

H302, H315, H319

References & Citations

[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Available Sizes

Frequently Asked Questions

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