Ethynyl Estradiol-d4

Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol; Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[350820-06-3]

Product Name Alternative

17α-Ethynylestradiol-d4; Ethynylestradiol-d4

UNSPSC

12352005

Hazard Statement

H302, H350

Target

Endogenous Metabolite; Estrogen Receptor/ERR

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology; Cancer

Purity

99.00

Solubility

DMSO : 250mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

C[C@@]12[C@](CC([2H])([2H])[C@@]2(O)C#C)([H])[C@@]3([H])[C@](C4=CC([2H])=C(O)C([2H])=C4CC3)([H])CC1

Molecular Formula

C20H20D4O2

Molecular Weight

300.43

Precautions

H302, H350

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Djerassi C. Chemical birth of the pill. 1992. Am J Obstet Gynecol. 2006 Jan;194 (1) :290-8.