3-Picolylamine

3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204) . 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) [1][2].

Product Specifications

CAS Number

[3731-52-0]

Product Name Alternative

Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine

UNSPSC

12352005

Hazard Statement

H290, H314

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-picolylamine.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NCC1=CC=CN=C1

Molecular Formula

C6H8N2

Molecular Weight

108.14

Precautions

H290, H314

References & Citations

[1]Park Y, et al. Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Sep 23;63 (10) :e01006-19.|[2]BLASCHKO H, et al. Potentiation of the response to histamine by picolylamines. Br J Pharmacol Chemother. 1962 Dec;19 (3) :544-51.