FWM-1
FWM-1 is a potent SARS-COV-2 NSP13 helicase enzyme inhibitor with binding free energy equals -328.6 kcal/mol. FWM-1 effectively disrupts the binding of ATP to the SARS-COV2 helicase enzyme[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fwm-1.html
Concentration
10mM
Purity
95.0
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
O=C1NC(NC(O)=C1C(C2=C(NC(NC2=O)=S)O)C3=CC=C(C=C3)Cl)=S
Molecular Formula
C15H11ClN4O4S2
Molecular Weight
410.86
References & Citations
[1]El Hassab MA, et al. Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :563-572.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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