ALDH1A3-IN-3

ALDH1A3-IN-3 is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate which limits its application as a selective inhibitor. ALDH1A3-IN-3 can be used for the research of prostate cancer[1].

Product Specifications

CAS Number

[18962-05-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aldehyde Dehydrogenase (ALDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aldh1a3-in-3.html

Purity

99.26

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)OC1=CC=C(C=O)C=C1

Molecular Formula

C10H12O2

Molecular Weight

164.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Ibrahim AIM, et, al. Expansion of the 4- (Diethylamino) benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65 (5) :3833-3848.