Arg-AMS
Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1].
Product Specifications
CAS Number
301351-95-1
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Arg-AMS.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCCNC(N)=N)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
Molecular Formula
C16H26N10O7S
Molecular Weight
502.51
References & Citations
[1]Kasai S, et al. Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling. Chem Commun (Camb) . 2015 Nov 11;51 (87) :15764-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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