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Arg-AMS

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1].

Product Specifications

CAS Number

301351-95-1

UNSPSC

12352005

Target

Aminoacyl-tRNA Synthetase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Arg-AMS.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCCNC(N)=N)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1

Molecular Formula

C16H26N10O7S

Molecular Weight

502.51

References & Citations

[1]Kasai S, et al. Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling. Chem Commun (Camb) . 2015 Nov 11;51 (87) :15764-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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