Jarin-1

Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants[1][2].

Product Specifications

CAS Number

[1212704-51-2]

Product Name Alternative

Amphetinile; CRC 82-16,CP 526555

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/jarin-1.html

Purity

99.17

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C3=O)=CC=C4N3C[C@]5([H])CN(C(CCOC)=O)C[C@@]4([H])C5

Molecular Formula

C28H29N3O4

Molecular Weight

471.55

Precautions

H315, H319, H335

References & Citations

[1]Delgado LD, et al. Application of a JA-Ile Biosynthesis Inhibitor to Methyl Jasmonate-Treated Strawberry Fruit Induces Upregulation of Specific MBW Complex-Related Genes and Accumulation of Proanthocyanidins. Molecules. 2018 Jun 13;23 (6) . pii: E1433.|[2] Meesters C, et al. A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana. Nat Chem Biol. 2014 Oct;10 (10) :830-6.