Afatinib-d6
Product Specifications
UNSPSC Description
Afatinib-d6 is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].
Target Antigen
Autophagy; EGFR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy;JAK/STAT Signaling;Others;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H]
Molecular Weight
491.98
References & Citations
[1]Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Clinical Information
No Development Reported
CAS Number
1313874-96-2
Available Sizes
Curated Selection
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