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EXP3179 (Standard)

EXP3179 (Standard) is the analytical standard of EXP3179. This product is intended for research and analytical applications. EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX) -2. EXP3179 exerts potent anti-inflammatory actions[1].

Product Specifications

CAS Number

114798-36-6

Product Name Alternative

Losartan Carboxaldehyde (Standard) ; DuP 167 (Standard)

UNSPSC

12352005

Target

COX; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/exp3179-standard.html

Smiles

[H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(C=C3)CN4C(C([H])=O)=C(N=C4CCCC)Cl

Molecular Formula

C22H21ClN6O

Molecular Weight

420.89

References & Citations

[1]Rossi GP. Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?. Hypertension. 2009;54 (4) :710-712.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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