(S, S) -J-113397

(S, S) -J-113397 is an isomer of J-113397 (HY-114072) . J-113397 is an Opioid Receptor antagonist[1].

Product Specifications

CAS Number

[256640-46-7]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-s-j-113397.html

Purity

99.87

Solubility

10 mM in DMSO

Smiles

O=C1N([C@@H]2[C@H](CN(CC2)CC3CCCCCCC3)CO)C4=CC=CC=C4N1CC

Molecular Formula

C24H37N3O2

Molecular Weight

399.57

References & Citations

[1]Kawamoto H, et al. Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[ (3 R, 4 R) -1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2 H-benzimidazol-2-one (J-113397) [J]. Journal of medicinal chemistry, 1999, 42 (25) : 5061-5063.