S-15535

S-15535 is a highly selective 5-HT1A receptor ligand. S-15535 is an antagonist of postsynaptic 5-HT1A receptors and an agonist of presynaptic 5-HT1A receptors. S-15535 can be used in research on psychiatric disorders, such as anti-anxiety[1].

Product Specifications

CAS Number

[146998-34-7]

Product Name Alternative

WX-UK1; UKI-1C,BYK61359

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-15535.html

Purity

99.82

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

N1(CCN(CC1)C2CC3=C(C2)C=CC=C3)C4=C5OCCOC5=CC=C4

Molecular Formula

C21H24N2O2

Molecular Weight

336.43

Precautions

P261-P280-P302+P352

References & Citations

[1]Millan MJ, et al. S 15535: a highly selective benzodioxopiperazine 5-HT1A receptor ligand which acts as an agonist and an antagonist at presynaptic and postsynaptic sites respectively. Eur J Pharmacol. 1993 Jan 5;230 (1) :99-102.