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aPKC-IN-1

Product Specifications

UNSPSC Description

aPKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].

Target Antigen

PKC

Type

Reference compound

Related Pathways

Epigenetics;TGF-beta/Smad

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/apkc-in-1.html

Smiles

O=C(C1=C(N)SC=C1C2=CC(OC)=C(OC)C=C2)OCC

Molecular Weight

307.36

References & Citations

[1]Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3034-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131220/aPKC-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131220/

Clinical Information

No Development Reported

CAS Number

15854-12-3

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