APKC-IN-1
APKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].
Product Specifications
CAS Number
[15854-12-3]
UNSPSC
12352005
Hazard Statement
H302-H318
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/apkc-in-1.html
Smiles
O=C(C1=C(N)SC=C1C2=CC(OC)=C(OC)C=C2)OCC
Molecular Formula
C15H17NO4S
Molecular Weight
307.36
Precautions
P264-P270-P280-P330-P501
References & Citations
[1]Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23 (10) :3034-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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