APKC-IN-1

APKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].

Product Specifications

CAS Number

[15854-12-3]

UNSPSC

12352005

Hazard Statement

H302-H318

Target

PKC

Type

Reference compound

Related Pathways

Epigenetics; TGF-beta/Smad

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/apkc-in-1.html

Smiles

O=C(C1=C(N)SC=C1C2=CC(OC)=C(OC)C=C2)OCC

Molecular Formula

C15H17NO4S

Molecular Weight

307.36

Precautions

P264-P270-P280-P330-P501

References & Citations

[1]Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23 (10) :3034-8.