BMS-538305 (hydrochloride)
Product Specifications
UNSPSC Description
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bms-538305-hydrochloride.html
Smiles
O=C(N1[C@@H]2[C@H](CC1)C2)[C@H]([C@@]34C[C@@](C[C@H](C[C@H]5C4)C3)(C5)O)N.Cl
Molecular Weight
326.86
References & Citations
[1]Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120631A/BMS-538305-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120631A/
Clinical Information
No Development Reported
CAS Number
841302-51-0
Curated Selection
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