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L-Palmitoylcarnitine

L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

Product Specifications

CAS Number

2364-67-2

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; Potassium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/L-Palmitoylcarnitine.html

Purity

99.88

Solubility

Ethanol : 25 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O

Molecular Formula

C23H45NO4

Molecular Weight

399.61

Precautions

H315, H319, H335

References & Citations

[1]Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K (ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441 (2-3) :200-207.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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