Aleniglipron
Aleniglipron (compound 121a) (GSBR-1290) is a GLP-1 agonist with an EC50 value of less than 0.1 nM in the HDB cell line in a cAMP stimulation assay[1].
Product Specifications
CAS Number
[2685823-26-9]
Product Name Alternative
GSBR-1290
UNSPSC
12352005
Target
GLP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aleniglipron.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@H]1[C@](N2C3=CC=C(C4CCOCC4)C=C3C=C2C(N5[C@H](C6=C(N7C(N(C8=CC(NC)=C(C=C8)P(CC)(CC)=O)C=C7)=O)N(C9=CC(C)=C(C(C)=C9)F)N=C6CC5)C)=O)(C%10=NOC(N%10)=O)C1
Molecular Formula
C49H55FN9O6P
Molecular Weight
915.99
References & Citations
[1]Qinghua Meng, et al. Heterocyclic glp-1 agonists. WO2023016546. 2022-08-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
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Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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