P-gp inhibitor 25
P-gp inhibitor 25 (compound 16c) is a P-gp inhibitor. P-gp inhibitor 25 can enhance the oral absorption of paclitaxel. P-gp inhibitor 25 can be used in anti-cancer research[1].
Product Specifications
CAS Number
3031431-31-6
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p-gp-inhibitor-25.html
Smiles
O=C(C1=CC2=CC=CC=C2N=C1)NC3=CC(OC)=C(OC)C=C3C(NC4=CC=C(/C=C/C(N5CCC6=C(OC7=CC(OC)=C(OC)C=C76)C5)=O)C=C4)=O
Molecular Formula
C41H36N4O8
Molecular Weight
712.75
References & Citations
[1]Zhou X, et al. Highly Potent and Intestine Specific P-Glycoprotein Inhibitor to Enable Oral Delivery of Taxol. Angew Chem Int Ed Engl. 2024 Aug 13:e202412649.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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