Tiaramide (hydrochloride)

Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release[1][2].

Product Specifications

CAS Number

[35941-71-0]

Product Name Alternative

RHC 2592-A

UNSPSC

12352005

Hazard Statement

H318

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tiaramide-hydrochloride.html

Purity

98.70

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1SC2=CC=C(Cl)C=C2N1CC(N3CCN(CCO)CC3)=O.Cl

Molecular Formula

C15H19Cl2N3O3S

Molecular Weight

392.30

Precautions

H318

References & Citations

[1]Khandwala A, et al. Antiallergic activity of tiaramide (RHC 2592-A) . Int Arch Allergy Appl Immunol. 1982;69 (2) :159-68. |[2]Noguchi H, et al. Disposition and metabolic fate of tiaramide hydrochloride, a new anti-inflammatory agent, in the rat. Xenobiotica. 1977 Aug;7 (8) :491-503.