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ART615

ART615 is the related isomer of ART558. ART615, the inactive of ART558, elicits 50=7.9 nM) [1].

Product Specifications

CAS Number

3031765-75-7

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/art615.html

Purity

98.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H]1N(C2=NC(C)=CC(C(F)(F)F)=C2C#N)C[C@H](O)C1)N(C)C3=CC=CC(C)=C3

Molecular Formula

C21H21F3N4O2

Molecular Weight

418.41

References & Citations

[1]Zatreanu D, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17;12 (1) :3636.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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