ART615
ART615 is the related isomer of ART558. ART615, the inactive of ART558, elicits 50=7.9 nM) [1].
Product Specifications
CAS Number
[3031765-75-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/art615.html
Purity
98.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1N(C2=NC(C)=CC(C(F)(F)F)=C2C#N)C[C@H](O)C1)N(C)C3=CC=CC(C)=C3
Molecular Formula
C21H21F3N4O2
Molecular Weight
418.41
References & Citations
[1]Zatreanu D, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17;12 (1) :3636.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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