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CXCL2 rabbit pAb

Function: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity. online information: CXCL2 entry, pharmaceutical: GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias. PTM: The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. similarity: Belongs to the intercrine alpha (chemokine CxC) family.

Product Specifications

Background

Function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity., online information:CXCL2 entry, pharmaceutical:GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias., PTM:The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells., similarity:Belongs to the intercrine alpha (chemokine CxC) family.

Synonyms

C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)]

Gene ID

2920

UniProt

P19875

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human GROβ AA range: 58-107

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20286-1.pdf

Subcellular Location

Secreted.

Other Product Names

C-X-C motif chemokine 2 (Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha) [Cleaved into: GRO-beta (5-73; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353) ]

Gene ID (Human)

2920

SwissProt (Human)

P19875

Available Sizes

Curated Selection

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