FKBP51-Hsp90-IN-2
FKBP51-Hsp90-IN-2 (Compound E08) is a selective FKBP51-Hsp90 protein-protein interaction inhibitor with IC50 values of 0.4 µM and 5 µM for FKBP51 and FKBP52, respectively. FKBP51-Hsp90-IN-2 also effectively stimulates cellular energy metabolism and neurite growth. FKBP51-Hsp90-IN-2 can be used in research on neurodegenerative diseases and cancer[1].
Product Specifications
CAS Number
601511-07-3
UNSPSC
12352005
Target
FKBP; HSP
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fkbp51-hsp90-in-2.html
Solubility
10 mM in DMSO
Smiles
CCC(NC1=C(C=C(C=C1)NC(CSC2=NC3=CC4=C(C=C3C=C2C)CCC4)=O)C)=O
Molecular Formula
C25H27N3O2S
Molecular Weight
433.57
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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