Recombinant Human soluble CD40 Ligand (rHu sCD40L)
Product Specifications
CAS Number
9000-83-3
Synonyms
TNFSF5, sCD40L, CD154, gp39, T-BAM, TNF-related Activation Protein, TRAP
Source
Escherichia coli.
Purity
> 95 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.
Molecular Weight
Approximately 16.3 kDa, a single non-glycosylated polypeptide chain containing 149 amino acids.
Storage Conditions
This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.0.
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